FUNDED PROJECTS

SOLUTIONS FOR HERNIA SURGERY (Funded over 2015-2017)

Tissuegraft has developed a patch for hernia containing, derived from decellularized bovine pericardium. The patch has the advantage of high bioactivity, in order to minimize infection risk and ensure optimal integration with abdominal wall tissues. This advantage enables an adequate surgical site regeneration avoiding erosion and tissue adhesion events. Thus, the patch guarantees a better comfort for patient because of the absence of chronical pain and a faster healing and regeneration of the tissue.

SOLUTIONS FOR VASCULAR SURGERY (Funded over 2016-2018)

Tissuegraft is realizing biological vascular substitutes meant for creation of artificial peripheral vascular accesses or repair/ substitution of small vascular sections (coronary bypass, vascular wall repair). The advantages are represented by perfect haemocompatibility, a fast integration at the implant site, and long lasting. The vascular substitutes are derived from decellularized porcine blood vessels. The activation and functionalization process involved by TissueGraft innovative technique allows the reinforcement of vascular matrix.

RENAL PARENCHYMA (2018-in progress)

TissueGraft is studying the development of a decellularized matrix derived from small animals kidney. The purpose of this matrix is to obtain a substrate that mimics the characteristics of living kidney, for ex vivo models of renal pathologies.

LIVER PARENCHIMA (2018-in progress)

TissueGraft is studying the development of a decellularized matrix derived from small animals liver. The purpose of this matrix is to obtain a substrate that mimics the characteristics of living liver, for ex vivo models of hepatic pathologies.

PLASMA TREATMENT ON DECELLULARIZED MATRICES (2019-in progress)

Collaborative research development project with the partnership of Plasmionique, Inc, company, regarding the effect of plasma treatments on natural materials – in particular polysaccharides and collagen – for biotechnologicla applications in health. The project is funded by the Natural Science and Engineering Research Council of Canada and the Government of Quebec.